Animals 100ml Flunixin Meglumine Injection

[Veterinary drug name]                         OTC

Generic name: Flunixin Meglumine Injection

Trade name:

English name :Flunixin Meglumine Injection

Chinese Pinyin :Funixin Pujia'an Zhusheye

[Main ingredient] Flunixin pujia 'an meglumine

[Properties]  This product is colorless or light yellow clear liquid.

[Pharmacological effects] Pharmacodynamics Flunixin meglumine is a powerful cyclooxygenase inhibitor with analgesic, antipyretic, anti-inflammatory and antirheumatic effects. Analgesic effects are caused by inhibiting the synthesis of peripheral prostaglandins or their pain sensitizing substances or their combined action, thus blocking the conduction of pain impulses. The anti-inflammatory effect of peripheral tissue may be caused by inhibiting cyclooxygenase, reducing the formation of prostaglandin precursor substances, and inhibiting the local inflammatory response caused by other mediators.

Pharmacokinetics After a single intramuscular injection (2.2mg/kg body weight), the plasma elimination half-life was 3 to 4 h, the peak concentration was 2.94μg/mL, the peak time was 0.4 h, and the drug was still detectable in the blood 18 h after administration. The apparent volume of distribution was 2.0L/kg, and the bioavailability was 87% after a single neck injection.

[Drug interactions] (1) Flunixin meglumine should not be used together with other non-steroidal anti-inflammatory drugs, because it will aggravate the toxic side effects on the gastrointestinal tract, such as ulcers, bleeding, etc.

(2) Due to the high binding rate of plasma protein, when combined with other drugs, flunixin meglumide may replace other drugs that bind to plasma protein or be replaced by other drugs, resulting in enhanced effects of the replaced drugs and even toxicity.

(3) Combined with antibiotics, it can be used for the adjuvant treatment of sows with aglactation syndrome.

[Action and use] antipyretic, analgesic and anti-inflammatory drugs. It is used for febrile, inflammatory diseases, muscle pain and soft tissue pain in domestic animals and small animals.

[Usage and dosage] intramuscular and intravenous injection: one dose, 0.4ml per 10kg body weight for beef cattle and pigs; 0.2 ~ 0.4ml for dogs and cats. Use once or twice a day for no more than 5 days.

[Adverse reaction] intramuscular injection has local irritating effect. Long-term use of large doses of this product may lead to gastric ulcer and renal injury in animals.

[Precautions] Use with caution in animals with digestive tract ulcers.

[Rest period] cattle and pigs 28 days.

[Specification]  As per C₁₄H₁₁F₃N₂O₂ (1)2ml: 100mg(2)5ml:250mg(3)10ml: 0.5g(4)50ml:2.5g(5)100ml: 5g

[Pack]  10ml*10 sticks *40 boxes or to order

[Storage] Block out light and store airtight